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Based on our observations that β-catenin itself is required for proliferation in cells with active β-catenin, we hypothesized that some of these genes may affect proliferation through regulation of β-catenin activity.
Since increased ROS may affect proliferation and cell survival, we next determined whether kd of MnSOD alters proliferation.
Since a systemic inflammatory response was present, we hypothesized that the products of inflammation, such as cytokines and growth factors, may affect proliferation in the mammary epithelium.
It may affect proliferation in MCF-7 cells by interfering with the estrogen receptor's ability to activate its downstream target genes (Ombra et al., 2013) or through other means (Muller et al., 2002).
All of these biologic processes may be closely related, and it may not be possible to separate them, as BMI-1 has also been found to be important for chromatin remodelling (Shao et al, 1999) and may affect proliferation by repressing the cyclin-dependent kinase inhibitors p16/INK4a and p14/ARF (Jacobs et al, 1999; Jacobs and van Lohuizen, 2002; Pasini et al, 2004; Liu et al, 2006).
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As CD3+ pan T cells were isolated and used for all experiments, it was necessary to measure the proportions of CD4+ and CD8+ T cells within these populations, as differences in these may also affect proliferation and also make the samples more heterogeneous.
To confirm whether TWEAK may affect the proliferation or apoptosis of kidney cells, we performed a cell proliferation assay.
This may suggest that randomization of the cell orientation performed by slow rotating clinostat has not the same effect on Paramecium as that under microgravity that may affect the proliferation as the result of the reduced cost of propulsion.
These results suggest that aging influences the microenvironment for adult and immature neurons in the brain, which may affect the proliferation and migration of neural stem/progenitor cells, and YKS has pharmacological potency for these age-related events.
One mechanism by which N-cadherin may affect cell proliferation is by interacting with LRP5/6 [39].
To determine whether IFN-γ may affect the proliferation of human and mouse MSCs through the activation of the KP and subsequent depletion of tryptophan from the extracellular milieu, cells were cultured in α-MEM containing 20% and 10% FBS respectively, in the presence of 100 IU/ml of IFN-γ; cell growth was then assessed in long-term cultures.
More suggestions(15)
may affect proliferative
may affect spread
may affect match
may facilitate proliferation
may control proliferation
may support proliferation
may induce proliferation
may affect chemotherapy
may change proliferation
may prevent proliferation
may drive proliferation
may affect wage
may promote proliferation
may limit proliferation
may mediate proliferation
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