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The VWF content of the substrate plasma may affect potency measurements of highly purified FVIII products in the one-stage assay 21.
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The deficiencies may affect the potency, purity or quality of the products, the agency said in a statement.
Experimentally, it has been shown that ΔΨ de-polarization may either deactivate or potentiate some GPCRs, and the effects may affect either potency (binding ability) or efficacy of the agonist.
It has been suggested that propofol may affect the potency of neuromuscular blocking drugs.
DOI: http://dx.doi.org/10.7554/eLife.02076.009 We also considered the possibility that the length of the climbing fiber-triggered pause in simple spike firing may affect the potency of climbing fiber activity to induce learning (Maiz et al., 2012).
Oncologic surgery for prostate, bladder, or colon cancer may damage nerves and affect potency or ejaculation.
Some of the conditions that affect potency are heat, moisture and humidity.
On the other hand, the authors also observed complex and large self-assembly structures, largely driven by the long and saturated palmitoyl chains, which may affect the antimicrobial potency of these lipopeptides, particularly at temperatures below the melting temperature of palmitic acid (63 64°C) [55].
Lipophilicity may affect the analgesic potency of intrathecally administered agents (Eisenach et al., 1994).
The voltage protocol and temperature may affect the estimation of drug potency, but limited information is available in this regard.
The induction of cytochrome P450 (CYP) by sucralose reemphasizes the concern that this organochlorine sweetener (and perhaps some other high-potency sweeteners) may affect the bioavailability of coadministered drugs through sweetener drug interactions involving metabolic enzymes.
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