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Exact(5)
Changes in PfCRT may affect parasite transport ability; and alteration in the activities of other transporters may be necessary for the parasite survival.
Additionally, parasite growth from one to two cycles in the presence of human immune plasma could select for merozoite antigenic variation that may affect parasite invasion efficiency [40], [47] [49] Thus comparison of different GIA must take cycle number into consideration.
These characteristics may affect parasite host interaction and limit GP63 protease activity in L. (Sauroleishmania) tarentolae, as has been previously suggested [ 7].
In addition, other parameters, including red cell phenotypes, drug quality, and pharmacokinetic profiles can differ between patients and may affect parasite clearance.
Polyparasitism may also be likely to have a large impact on both the parasites and the host involved as it may affect parasite growth, maturation, reproductive success and survival along with the susceptibility, morbidity and immune response of the host (Keusch and Migasena 1982).
Similar(54)
In addition behavioural adaptations may also affect parasite population structure, thereby potentially reducing parasite intensity [ 1], and ultimately their evolutionary potential, classically defined as the ability to incorporate genotypes able to outcompete those put forward by the opponent [ 4].
While during trophozoite stage it may affect the parasite DNA replication by modulating the DNA binding activity of replication factors, parasites from other stages (ring/schizont) may be affected by the inhibition of transcription, recombination, and many other DNA mediated processes that require proper DNA protein interaction.
Mutations in PfCRT may affect the parasite growth or survival.
According to sharing of immune-compromising mechanisms of both infections with Leishmania infantum and HIV-1 that may affect the parasite control in visceral leishmaniasis coinfected patients [ 42].
With the discovery of G-quadruplex forming sequences in the genome of P. falciparum, it can be hypothesized that these ligands may also have the potential to affect parasite gene expression by stabilizing G-quadruplexes located in gene promoter regions.
The truncation of these genes, likewise, appeared not to affect parasite growth, suggesting that expression of these genes may not be essential for the asexual blood stage development.
Related(20)
may influence parasite
may affect respiratory
may affect infection
may affect social
may increase parasite
may affect vulnerable
may promote parasite
may limit parasite
may indicate parasite
may reflect parasite
may include parasite
may make parasite
may affect clinical
may shape parasite
may prevent parasite
may affect individual
may affect early
may affect EPCs
may undercut parasite
may reduce parasite
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