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Different enforcement techniques, traditions, and even cultures may affect overall results as well as imposing substantial costs for all involved.
The development of novel site-specific conjugation technologies enables the systematic study of architectural features within the antibody conjugated drug linker that may affect overall therapeutic indices.
The methylation status of the promoter or the enhancer regions of the O6-methylguanine methyltransferase (MGMT) gene may impact the efficacy and sensitivity of temozolomide, and hence may affect overall patient survival.
Moving the site more frequently also results in higher traffic management costs and may affect overall safety and capacity.
"This new architecture provides a way to circumvent traditional security controls by exploiting equipment in the edge of the network – exploitation which may affect overall network integrity and availability, as well as the confidentiality of customer data.
Additionally, instead of underthrust sediment-filled graben blocks being only vertically loaded, initial sediment accretion may affect overall sediment porosity due to the addition of both vertical and horizontal strains on the subducting sediment (e.g., Moore et al. 2011).
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Patients with co-morbidities may be more likely to initiate ART at hospital level and also to have poorer outcomes, therefore these are potential confounders which may negatively affect overall outcome estimates at hospital level compared to PHC sites.
Furthermore, removal of the primary tumour may positively affect overall survival.
These changes may not only affect overall muscle function, but may especially impact the ability to stabilize standing balance in the frontal plane.
Findings indicate that, dependent upon study goals, researchers' choice of design may influence participant recruitment, participant commitment, and impact on staff, factors that may in turn affect overall study success.
Non-catalytic gas solid reactions are examined, where both pore diffusion and chemical kinetics may affect the overall rate.
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CEO of Professional Science Editing for Scientists @ prosciediting.com