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Both SNPs are located in the 5′ regulatory region, which may affect nascent mRNA production or protein expression, thereby modulating HIV-1 production.
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Hence, it is important to understand how Hdacs1,2 function during replication and how these HDACs affect nascent chromatin.
Therefore, we concluded that changes in the amount of Ca2+ influx and/or a re-distribution of Ca2+ entry may affect the survival of nascent neurons.
These results suggest that changes in the amount of depolarization-induced Ca2+ influx may affect the survival of nascent neurons, although the role of a possible re-distribution of Ca2+ entry through different spine categories cannot be excluded.
Interactions between the nascent protein and the translocon tunnel may affect the conformation of 2A within the ribosome exit tunnel and, in consequence, the C-terminal tight-turn of 2A in the peptidyl-transferase centre itself - inhibiting the 2A reaction.
Signals in the DNA or RNA may affect RNA elongation; for example, both a hairpin structure in the nascent RNA and a run of uridines at the 3′ end of a transcript interfere with elongation and promote transcription termination (Bengal and Aloni 1989; Keene et al. 1999; Palangat et al. 1998).
ERAP1 may affect disease risk either through its function to trim peptides prior to loading into nascent HLA class I molecules, or alternatively through its role in cleaving pro-inflammatory cytokine receptors from the cell wall, including TNF receptor 1, IL-1 receptor 2 and IL-6 receptor.
Altering nucleosome density may affect both RNAP II elongation kinetics and polyadenylation, or the recruitment of the polyadenylation machinery to the nascent transcript [ 24, 25].
That may affect their play.
"We may affect the bacteria".
This may affect vulnerable people.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com