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Because age, sex, smoking status and study phase may affect methylation levels, the methQTL analysis adjusted for these variables.
Several factors related to general health may affect methylation ability.
This may affect methylation, oxidation and cellular energy availability, respectively, even though expression level differences are significant but small.
Additional adjustment for asthma, allergy, and wheeze were evaluated, because presence of disease may affect methylation status.
In addition, OGT-mediated O-GlcNAcylation of HCF1 may affect methylation of histone 3 lysine 4 residue (H3K4), as HCF1 is an integral component of SET1/COMPASS, a major H3K4 methyltransferase complex.
All tissue samples were obtained from the right ventricular myocardium tissues immediately after surgical resection or autopsy and stored in RNAlater® (AMBION, Inc., Austin, TX, U.S). until use to exclude any tissue heterogeneity that may affect methylation results.
Similar(52)
The aim of this study was to evaluate whether environmental cadmium exposure, mainly through the normal diet, may affect DNA methylation, both of repetitive genetic elements (as a proxy for global methylation) and of specific genes.
How gene-body methylation may alter the gene expression, or alternatively how expression level may affect the methylation level, is still not clear.
Furthermore, while a SNP in the probe body may affect the methylation readout for the CpG, a SNP at the interrogated CpG is affecting the methylation status of that exact location in the genome that is being interrogated.
Oxidation of DNA may affect DNA methylation due to oxidation of DNA at either the methylated cytosines or guanines in CpG sequences.
The aim of this study was to evaluate the possibility that polymorphic variants of genes that may affect DNA methylation status are associated with the risk of cervical cancer in the Polish population.
More suggestions(15)
may modulate methylation
may affect wage
may decrease methylation
may allow methylation
may be methylation
may affect detector
may increase methylation
may affect friction
may affect location
may undergo methylation
may acquire methylation
may alter methylation
may affect student
may direct methylation
may include methylation
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