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Classical applications of bioactive glasses involve bone filling materials and dental implants; however, the fascinating question to be answered in the next few years is: how can bioactive glasses be useful in soft tissue regeneration and to treat diseases, such as tumours, that may affect internal organs?
Differing LTFU between study groups may affect internal validity and generalizability of the results.
Reactions to sulfasalazine are believed to arise because of an idiosyncratic delayed-type hypersensitivity reaction that may affect internal organs variably.
The condition is usually mild, but some patients may have severe disease that may affect internal organs or lead to secondary bacterial infections [ 9].
This condition is called disseminated zoster, and it may affect internal organs as well as joints.
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In trials testing emergency department (ED) interventions, migration of emergency physicians (EPs) between hospitals is an important concern, as contamination may affect both internal and external validity.
"Eating inconsistently may affect our internal body clock," she says.
EHRs suffer from data quality problems [ 11- 13], which may affect the internal validity of retrospective studies.
Other limitations of population-based studies also apply, including selection and non-response bias, which may affect the internal and external validity of our findings.
While TNF signaling through TNFR2 may affect the internal sensitivity of β cells to cell death, TNFR2 activation of NF-kB may act primarily to induce cellular changes that promote islet inflammation and susceptibility to CTL killing.
Thus, its different sample size may affect the internal and external validity of this study, though the samples of both periods were based on the same stratified probability-sample design.
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CEO of Professional Science Editing for Scientists @ prosciediting.com