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They also suggest that a wide variety of conditions and factors, capable of inducing heat shock gene expression and the stress response, may affect genome stability, a conclusion with broad implications for our understanding of processes leading to oncogenesis.
Delivery of transcriptional factors may affect genome stability, while small-molecule compounds may require more evaluations when applied in vivo.
Similar(58)
Additionally, the genes within the NOD fragments may affect gene expression elsewhere in the genome.
Phytochemicals may affect the genome and trigger damage to DNA and repair mechanisms [ 31].
In that sense, one can also say that proteins exert a selective process on the base composition of DNA at the CDS level and that this selective process may affect the genome organization according to the mutational bias toward GC or AT and other selective processes according to the functional necessities of coding DNA in relation to non-coding DNA (see Bernardi 11 and Kudla et al. 50).
In the present context, it may affect gene family evolution by exchanging sequence motifs among family members within a genome, affecting their identities and phylogenetic relationships.
Regarding important functions of H2A.Z, many efforts have been spent on identifying genomic signatures that may affect its genome-wide distribution.
Taken together, these findings indicate that changes in the nucleolus that affect genome integrity may modulate CLS in yeast.
Instances of environmentally induced mutations have been documented in bacteria [ 21], and a similar process may affect the mitochondrial genome.
Genomic arrangement in our genome may affect the expression regulation of different genes, thus understanding of the genomic structures may help us better understand gene expression regulation and gene function.
At the center of this controversy is the issue of whether or not insertion of a transgene into the host plant genome or manipulation of an allele in the host genome may affect the expression of other genes and ultimately lead to unintended phenotypes.
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