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Hence, it seems plausible that foods may affect endogenous levels of anandamide and its effects.
As neomycin resistance gene (Neo) is used in our targeting construct and its expression is driven by a strong promoter, insertion of the neo cassette in an intron may affect endogenous gene expression and may result in the inactivation or reduction of the floxed genes.
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To our knowledge these data would indicate that protein folding may affects endogenous class I restricted T cell epitope generation.
We cannot exclude, however, that overexpression of the ABD of βI-spectrin may negatively affect endogenous spectrin or induce other downstream compensatory effects [30].
However, such clamp techniques are not feasible in the rapidly changing ICU environment and may in themselves affect endogenous insulin secretion.
Introduction of antioxidants in the diet may affect the endogenous antioxidant system and the effect is not always advantageous.
The observed 30.4% ciliary localization is likely to be an underestimation, as steric interference from the C-terminal GFP tag may affect the endogenous pattern of protein localization.
Mexican guidelines require immunological testing and reporting, including for hypersensitivity, infusion reactions, and effects on efficacy for any product where an immune response may affect the endogenous protein or its biological function.
While EDCs initially referred to substances interfering with reproductive hormones, the term now extends to compounds that may affect any endogenous hormones that carry signals from one cell to another, and there are now about 900 chemicals characterized as EDCs.
However, the endogenous antioxidant catalase is a reported target of selective autophagy [ 22] and we suspect that autophagy inhibition may affect levels of endogenous antioxidants.
Using the cell lysate depicted in Figure 3a, we assessed how MSH2Y238F may affect the interaction of endogenous MSH2 with NPM-ALK.
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