Sentence examples for may affect effectors from inspiring English sources

Thus, exposure to EDCs at this early stage of development may affect effectors of the immune response.

On the other hand, a mutation-induced conformational change may directly affect effector engagement, as has been proposed for H-ras (Abankwa et al., 2008a) and shown for K-ras on nanodiscs (Mazhab-Jafari et al., 2015).

In light of our results, we suggest that the inhibition of Tim-3/Gal-9 pathway may affect the effector function of different leukocyte subsets.

In another study, with different B lymphocytes subpopulations, in normal and chronic proliferative disorders, it was suggested that a disturbed expression of IL-18 and/or of its receptor on neoplastic B cells could in certain cases facilitate the growth of tumors, as they may affect antitumor effector mechanisms because of poor regulation of IL-18 production [ 27].

Our results indicated that these RdDM effectors may affect siRNA abundance mainly through their function together with RNAP V at certain RdDM target loci.

Firstly, geohelminth infections have been consistently associated with a reduced prevalence of SPT [ 24] although the prevalence of allergen-specific IgE may not be affected [ 25], indicating that geohelminths may affect the ability of effector cells such as mast cells to respond to an allergen stimulus rather than the process of allergen sensitization.

Allergens, often otherwise harmless compounds, thus represent one of the key components of the disease and measures that alter their ability to activate effector cells may affect allergic disease conditions.

These genes may play roles in regulating effector secretion or may affect Congo red binding through a mechanism independent of T3SA function.

Our analyses demonstrate that genomic alterations may affect multiple pathways, which could be classified as drug effector and non-effector pathways by the way they target the two cancer hallmarks 'sustaining proliferative signaling' and 'evading growth suppressors' [21].

Blocking TGF-β signaling did not affect effector function of CD8+ T cells.

These assays potentially assess the longer-term interactions of effector and target cells, which may affect target cell survival through processes such as the induction of apoptosis through cytokine activity or death receptor activation.