Sentence examples for may affect dna from inspiring English sources

Thus, expression of Rpn4*, while not directly affecting checkpoint activation, reduces the viability of checkpoint mutants in response to DNA damage, suggesting that inhibition of Rpn4 degradation may affect DNA repair.

Thus we speculated that NFBD1 may affect DNA repair via the NHEJ pathway through its direct interaction with DNA-PK, while the main mechanism of NFBD1 in HR may be mediated by the regulation of Rad51 stability, which affected its recruitment to DSBs and subsequent repair.

With respect to genetic factors, a number of polymorphisms in various DNA repair genes have been discovered, and it is possible that these polymorphisms may affect DNA repair capacity and thus modulate susceptibility to cancer.

Single nucleotide polymorphisms (SNPs) located in genes encoding enzymes of the folate and choline metabolism may affect DNA methyltransferase activity.

The aim of this study was to evaluate the possibility that polymorphic variants of genes that may affect DNA methylation status are associated with the risk of cervical cancer in the Polish population.

Therefore, BRAFV600E may affect DNA hypermethylation of MLH1 but only in certain circumstances.

Abnormal DNA methylation may affect DNA-protein interactions and so may alter all processes in which such interactions occur.

Since the rAAV genome is linear and single stranded DNA, the viral infection may affect DNA-PK activity [56], [57], [58].

The change in D0774 AmrR may indirectly affect DNA binding to the transcription factor [ 22], while the large insertion within D2910 amrR likely inactivates the repressor altogether.

We note that such drugs and cellular heterogeneity of the studied samples [ 53] may also affect DNA methylation [ 54] as confounding factors.

For most POPs, estimates in the third tertile were statistically significant for the Alu assay but not the for the LINE-1 assay (data not shown) In vitro and animal studies have suggested that exposure to endocrine disruptors, such as POPs, may adversely affect DNA methylation patterns (Anway et al. 2006; Anway and Skinner 2006; Chang et al. 2006; Kang and Lee 2005).