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The various genes in the network may affect distinct processes while converging to generate the SM fate.
In this regard, a given LOH event may affect distinct doses of transcription between diffuse- and intestinal-type gastric cancers that establish distinct gene expression patterns.
In addition, HDAC inhibition by TSA inhibits induction of IL-33 expression by TLR agonists but does not inhibit induction of IL-1β expression to similar degrees, suggesting that distinct pathways regulate expression of these two cytokines and that HDAC inhibition may affect distinct innate immune responses.
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Thus, selective pressures due to fishery harvest and nonretention mortality may affect discrete locally adapted populations with distinct morphologies in different ways (Burgner 1964; Hamon et al. 2000; Kendall and Quinn 2009).
Alternatively, progerin may induce stochastic epigenetic alterations that affect distinct gene sets, each of which contributes in distinct ways to the onset of the progeroid phenotypes.
Importantly, the mutations affect distinct processes required for germline formation.
Multi-vesicle assemblies of predefined architecture (cp. Figure 5) may affect at least three distinct domains.
This study provides a solid basis for the implementation of multi-vesicle assemblies that may affect at least three distinct domains.
Different types of fibre and/or fibre sources may affect metabolic health in distinct ways, and therefore the diversity of fibre sources in the food supply is important [ 8].
How this lesion specifically affects mitochondrial function or iron metabolism is unclear but it has been proposed that pseudouridylation of small RNA's distinct from tRNA may affect mitochondrial function [10].
First, the Snord116 deletion may affect gene expression only in a distinct population of cells or hypothalamic sub-regions, and the isolated hypothalami, although significantly smaller than whole brain (1/20 in weight), are still a crude mixture of multiple cell types.
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CEO of Professional Science Editing for Scientists @ prosciediting.com