Sentence examples for may affect distant from inspiring English sources

Thus, in T2DM, elevated amounts of heparanase are found in the circulation, spread systemically and may affect distant organs, tissues, and cells.

Based on the developmental origins of the health and disease hypothesis or fetal programming (4), the intrauterine environment represents a time when changes in maternal metabolism may affect distant metabolic dysfunction in the offspring mediated through physiological and/or epigenetic mechanisms.

The pain may be local, but may also affect distant areas of the knee [ 5] and become chronic in patients with OA [ 6].

However, despite these attractive speculations on the genes vicinal to the associated SNPs, it is possible that these variants may also affect distant as yet unidentified target genes.

Mbnl1−/− mice were analysed in two groups, data shown excludes individual mice that showed >10% thigmotaxis at the end of training as these mice may have visual complications that affect distant vision.

Even in healthy lungs, MV may contribute to a positive feedback loop that starts with mechanotransduction (in lungs) at the epithelial and endothelial levels leading to a deleterious inflammatory cascade that might affect distant organs and systems [ 4- 6].

Disruptions from SH in the periventricular region may affect communication between distant multiple cortical brain areas and may result in an overall decrease in speed of processing.

Hence, the ability of uPA/uPAR system to sustain elevated basal level of activated Erk may represent a mechanism whereby uPA/uPAR system may affect cancer progression and distant metastasis in vivo.

Moreover, IR emission from dust in the IGM accumulated from the distant Universe may affect the cosmic far-IR background and the cosmic microwave background (Aguirre and Haiman, 2000).

The shift in prognostic factors and molecular subtype was shown to be of clinical importance and indicated that biomarkers in the synchronous and asynchronous lymph nodes and distant metastases may affect the choice of treatment [ 9, 10].

Subsequently, we used this extended set and focused the posterior analyses on local eQTLs since they likely represent independent alleles, only affecting a single transcript and explaining a greater phenotypic variance, in contrast to distant eQTLs that may affect many genes and show minor phenotypic effects.