Sentence examples for may affect cartilage from inspiring English sources

In addition, this area is profoundly affected in osteoarthrosis and humoral mediators may affect cartilage matrix components via these communications.

Differential expression of these genes may affect cartilage matrix cross-linking, angiogenesis, energy metabolism, and growth regulation [ 12].

However, the research described above suggests that increases in endogenous ceramide may affect cartilage ECM protein transcription and translation, as well as activating degradative pathways that are involved in the pathogenesis of diseases such as osteoarthritis.

Injection of LPS (or any other inflammatory stimulus) into a joint will elicit a release of inflammatory mediators from both the synovial membrane and the articular cartilage, which may affect cartilage integrity and thus SF marker levels.

The biomechanical changes of the DN gel may affect cartilage regeneration and durability because the implanted DN gel, which was seen as a void space in the histology section, was remained surrounded by bone in the defect as it was but it is unknown whether the DN gel properly works as subchondral bone with similar biomechanical properties after inducing cartilage regeneration.

Because OA is a disease that involves all joint tissues, including cartilage, synovium and subchondral bone, the synovial inflammation may affect cartilage destruction; hence, the inhibitory effects of the NAMPT inhibitor FK866 on synovitis may contribute to the observed effects on cartilage destruction.

In addition to their possible role in the pathophysiology of joint disease, soluble mediators present in the joint may also affect cartilage repair, both in OA and in cartilage defect treatment [ 6, 7].

Dietary long-chain ω-3 PUFA may affect articular cartilage composition and appear to have beneficial effects in OA[ 5].

These results suggest that blocking NGF may affect joint cartilage via cell-mediated mechanism, in addition to the reported pain relief [ 15].

Exclusion criteria included being pregnant, having had diseases that may affect knee cartilage such as rheumatoid arthritis, or having a contraindication for MRI.

In alignment, other hormones that affect cartilage metabolism may be identified by a systematic screening of the response of bone resorption and cartilage degradation biochemical markers.