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Even though, supraphysiological levels of serum PRL may affect carcinogenesis.
Second, hyperglycemia may affect carcinogenesis, since increased glucose metabolism is one of the central characteristics of malignant tissues (4, 23).
The mechanism by which hormonal factors may affect carcinogenesis at different gynecological sites was considered as unclear.
ATP-binding cassette (ABC) transporters are abundant in the intestine and transport fatty acids, bacterial products, and dietary carcinogens, all of which may affect carcinogenesis.
Experimental evidence shows that malignant cell lines from, e. g., ovarian cancer and malignant melanoma also express ß-adrenoceptors and that catecholamine stress hormones may affect carcinogenesis through these receptors [ 2- 8].
Many environmental factors such as transport of mice, subtle strain-specific alterations in host inflammatory responsiveness, or breeding-colony-dependent differences in commensal microflora [ 41] may affect carcinogenesis [ 26, 27].
Similar(52)
It may prevent the carcinogenic effect of bile acids by creating insoluble salts, or it may directly affect carcinogenesis by decelerating cell proliferation.
Potentially, differences in microbiota of the skin may also affect carcinogenesis, as it was reported that skin resident commensals can strongly influence the local inflammatory milieu [ 28].
Evidence from prospective studies is beginning to show that energy intake in excess of expenditure, captured by a higher BMI, may affect prostate carcinogenesis and, in particular, risk of advanced disease, and that energy imbalance may function late in the carcinogenic pathway, therefore, facilitating progression rather than initiation of prostate tumours (Rodriguez et al, 2007).
As dietary intake may affect breast carcinogenesis over an extended period of time, to best represent long-term intake, we calculated cumulative averaged intakes of choline and betaine using repeated FFQ data for our primary analysis, to reduce measurement error in dietary assessment (Hu et al, 1999).
However, owing to the fact that each miRNA may regulate many target genes which can affect carcinogenesis in different ways, more studies are needed to investigate other miR-645 targets which may have critical roles in AGEJ tumorigenesis.
More suggestions(15)
may prevent carcinogenesis
may affect chemotherapy
may instigate carcinogenesis
may trigger carcinogenesis
may affect wage
may induce carcinogenesis
may initiate carcinogenesis
may potentiate carcinogenesis
may affect detector
may affect friction
may enhance carcinogenesis
may inhibit carcinogenesis
may affect location
may promote carcinogenesis
may impede carcinogenesis
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