Sentence examples for may affect apoptotic from inspiring English sources

Upon αB-crystallin R120G overexpression, amyloidogenic oligomers were detected in the heart, suggesting that toxic oligomers generated by this mutation may affect apoptotic pathways by inducing mitochondrial dysfunction and disrupting the cytoskeletal network [8], [12].

Therefore, one altered gene may affect multiple apoptotic pathways.

These genetic observations suggest that both the mutational status of PER2 S662 and the levels of PER2 protein may affect the apoptotic response to X-rays.

Tumourigenic aberrations to the post-translational control of Bid, such as its phosphorylation, cleavage or myristoylation, may affect its apoptotic potential (Desagher et al, 1999, 2001; Zha et al, 2000; Puthalakath and Strasser, 2002; Degli-Esposti et al, 2003).

The fact that both NUC-1 and CRN-6 affect apoptotic cells outside of their expression areas suggests that these two nucleases may be secreted (as predicted from their sequences; Figure S1A) and diffuse to other regions of the embryo to affect apoptotic DNA degradation.

While vps22 mutations cause strong non-autonomous overgrowth, they do not affect apoptotic resistance.

Mitochondrial fission and fusion can affect apoptotic cell death.

Due to our present findings that all tumors that are positive for p-p38 expression are also positive for Bcl-2, the relationship between p38 activation and Bcl-2 expression may be mediated by transcriptional and post transcriptional mechanisms, which may affect the anti-apoptotic Bcl-2 family proteins [ 43].

Naruse et al. (2006) discussed that the COX-2 selective NSAID meloxicam may affect a Bax-independent apoptotic pathway, which is yet to be elucidated [ 35].

Continuous exposure to a 60 Hz MF may affect biological processes including apoptotic cell death and spermatogenesis in the male reproductive system of mice in duration- and dose-dependent manner [ 21].

At early stages, apoptotic processes may affect cell functions without having immediate effects on cell viability.