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Fig 1B illustrates such a model, taking into account the possibility that in the basal state, the probe may adopt several conformations.
A comparison of the structures suggests that the conformation of the N-terminal segment is not highly restricted in the complex and may adopt several conformations.
While the model shows Thr-38 bound to the active site we believe that given the disordered nature of the loop it may adopt several alternative conformations that are similar in energy.
Recent advances in both clinical and laboratory research have reported that cancer cells may adopt several mechanisms against particular treatments including adjusting the signaling circuitry, activation of alternative pathways and cross-talks among various pathways to overcome the effects of inhibitors [ 1, 2].
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102L-129M PrP may be able to adopt several different pathogenic conformations, which may be permissible to a greater or lesser extent by the wild-type protein (Parchi et al., 1998; Hill et al., 2006).
Normal stem cells can adopt several different states (Fig. 2).
These papules or skin elevations can adopt several forms.
Topographical orientation relies on the integrity of several cognitive functions and different strategies that individuals may adopt while navigating in the environment.
The male may adopt a vertical or horizontal 'eagle display' with wings and tail spread wide and held still for several seconds.
In cases where basic models are insufficient, ecologists may adopt different kinds of statistical methods, such as the Akaike information criterion, or use models that can become mathematically complex as "several competing hypotheses are simultaneously confronted with the data".
We may adopt.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com