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In addition to its homeostatic role of maintaining low resting levels of intracellular calcium ([Ca2+](i)), the plasma-membrane calcium-ATPase (PMCA) may actively contribute to the generation of complex Ca2+ signals.
On one side, the brain is especially susceptible to damage during sepsis and on the other side the brain dysfunction may actively contribute to the pathogenesis of SE.
Collectively these functional analyses suggest that PPARG silencing may actively contribute to colon tumor progression.
Little is known, however, about intrathymic mechanisms that may actively contribute to thymus atrophy or initiate thymic recovery following stress events.
In addition, the changes of ISZ labeling induced by EE in PCs suggest that the presynaptic axons may actively contribute to the removal of ECM components.
However, the former may actively contribute to tumour formation.
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In addition, the definition of SGA may also actively contribute to reducing the discriminatory accuracy of the traditional risk factors since discrimination depends on the outcome and exposure.
In this study A. fumigatus may have actively contributed to iDC cell death through secreted molecules.
Recent reports indicate that CXCR4 is commonly expressed on NB metastasis in the bone marrow and that it may be actively contributing to NB tumour cell homing to the bone marrow [12].
We estimate that only a few thousand HSCs may be actively contributing toward blood regeneration at any time.
Since commensals may either passively or actively contribute to immune homeostasis, therapies aimed at selectively reducing the competitive advantage of pathogens may be effective supplements to traditional methods.
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