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It has been suggested that musclin may activate its specific receptors and NPR-C receptors in cardiovascular tissues and cells [ 9].
LSD2 may activate its target genes, possibly via its association with transcriptional elongation factors [ 28].
Another advantage of targeting TNF α is that reducing its level may activate its preconditioning function.
Hence our data support the hypothesis that RIN4 is a bonafide virulence target of AvrRpt2 and indicates that cleavage of RIN4 by AvrRpt2 may activate its ability to suppress PTI.
The activator of expression of amh in the chicken and other vertebrates is unclear, but is likely to involve the orphan nuclear receptor SF1 which is expressed in male gonads (ZZ) compared to females (ZW) suggesting that a dosed Z-linked gene such as dmrt1 may activate its expression in avians.
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For example, myostatin may inhibit a specific pathway, while PE may activate it.
Researchers suspect that the parasite competes with the virus for limited resources inside mosquito cells; Wolbachia may also activate its host's immune system, helping it fight subsequent infections.
We speculate that NPAS2-ARNTL/BmalI may regulate this gene as either an enhancer or a silencer and the implant placement may disproportionately activate its anabolic function.
It was also shown that caspase-3 may process and activate its own pro-form, albeit with significantly lower catalytic activity.
GFRa2 can also be shed from the membrane and may activate RET in its soluble form.
Syk may activate NLRP3 through its reported ability to interact directly with ASC, an adaptor for the assembly of the caspase-1 inflammasome (Shio et al., 2009).
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