Sentence examples for may act predominantly from inspiring English sources

Hence, it appears that in the longer term, the short-acting GLP-1 agonists may act predominantly by lowering postprandial glycemia (through a sustained, substantial inhibition of gastric emptying), while the long-acting GLP-1 agonists predominantly lower preprandial hyperglycemia through insulinotropic and glucagonostatic effects.

C2GnT-M may act predominantly as an inhibitor of early stages of colorectal carcinoma growth.

Enzymes, including the various proteases and chitinase, may act predominantly as aides in the digestion of prey.

These results suggest that non-parenchymal cells may act predominantly as coarse-grained controllers of liver regeneration, while hepatocyte responsiveness and miRNA or other regulation may act to achieve fine-tuned control of liver regeneration.

We have added text that frames this observation in the context of our previous work, which suggested as the reviewers noted that Foxp3 may act predominantly as a negative regulator of transcription (Arvey et al., Nature Immunology, 2014).

Whereas some cytokines that aggravate LN may act predominantly in a systemic fashion (for example, BAFF), other cytokines such as IL-17, IFNα and TGFβ have been shown to have a role in systemic autoimmunity as well as local renal disease.

We note that our additional assumption isreasonable for slow variables modulating currents that act predominantly to sustain orterminate activity.

SIP1 has been shown to act predominantly as transcriptional repressor but can also act as transcriptional activator in vivo [ 4- 8].

At the level of the vascular wall, CNP seems to act predominantly at the vein [ 123].

It is also important to note that whilst native GLP-1 may exert a regulatory role on CV biology through its interaction with the GLP-1R plus its independently cardioactive metabolite GLP-1 9-36 GLP-1 9-36 GLP-1 9-36onisynthetichielded from DPP-4 breakdown and therefore act predominantly via their action on the classical GLP-1R agonists5, 20].

In analogous experiments, the levels of low-molecular-mass thiols (<10 kDa, predominantly GSH), which may act as a competing target for the oxidant, were assessed; a dose-dependent loss of thiols was detected across the same oxidant concentration range.