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Cyclooxygenase inhibitors may act late or early in the pathway.
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The authors hypothesized that these drugs may act by disrupting late endosomal processing or by disrupting calcium signaling that is required for viral entry.
The putative di-leucine (L-L-X-X) motif at the C-terminus, which may act as a late endosomal/lysosomal targeting signal, is also conserved [ 9].
Thus, resveratrol may act as potential adjunctive treatment for late-stage hormone refractory prostate cancer.
In conclusion, our investigation identified that HMGB1 promotes neurovascular recovery via Rage and may act in the oxidized state in the late stage of SAH.
These studies demonstrating GLI1 may act as a tumor suppressor in the late stage of PDAC give insight into the disappointing results of clinical trials testing HH inhibitors in metastatic PDAC patients.
RbfA is thought to bind to the leader sequence and promote formation of h1 during the late stages of assembly, and may act synergistically with RimP to stabilize the central PK.
The effects of late-EPC exposure to prolonged hypoxia, which may act in vivo as a cofactor in the development of KS lesions, were evaluated in 2 patients.
Our data suggest that RAP-011 may act to rescue growth differentiation factor 11/Activin A-induced inhibition of late-stage erythropoiesis.
10Be-derived erosion rates are lower where late Quaternary neotectonic activity is reduced or absent, implying that 10Be concentration may act as a 'tracer' for disequilibrium landscapes responding to recent tectonism.
This review addresses some of the latest research developments on the exploitation of candidate adjuvant therapeutic agents that may act alongside conventional antibiotics as an alternative therapeutic strategy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com