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Although several studies have shown that MSCs may acquire differentiated phenotype, they lack functional activity of specialized cells [ 40, 41].
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During progression, tumours acquire differentiated characteristics reminiscent of specialized Mullerian duct epithelia, resulting in various histotypes of EOC.
Allied with poetry, however, it may acquire conceptual value.
A rogue regime may acquire a "multiple launch rocket system".
We hypothesize that SSEA3 expression is either identifying another less differentiated and/or tissue specific stem cell like population that is retrieved with the donor skin biopsy or that with culture, a subpopulation of fibroblasts may acquire the ability to express SSEA3.
First, MSC may acquire epithelial characteristics by reprogrammation.
Humans may acquire infection from potable water.
Indeed, cells have evolved regulatory networks to integrate environmental signals or acquired differentiated states that result in modulation of gene expression.
Similarly to cells obtained from colony-forming assays, Ddit3-transduced cells retained a GMP-like phenotype, while control cells acquired differentiated myeloid surface markers.
In this way, mesenchymal cells may again acquire a differentiated epithelial phenotype through a mesenchymal-to-epithelial transition, which might mean in terms of the metastatic process.
Regardless being stem cells, cancer cells, or normal differentiated cells, they may all acquire NS expression when in actively proliferating status.
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