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While the primary latent period of the virus does not vary with challenge strain nor vaccine treatment of host, the time until the maximum viral shedding rate is increased with vaccination.
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Input virus from the inoculum can not be detected for more than 6 hours after the inoculation, and viral shedding by infected animals reaches a maximum at 3 days (data not shown).
Clinical disease was also coupled with viremia and viral shedding.
Comment: Best sample may depend upon suspected viral infection and pathophysiology related to viremia, infected tissue and viral shedding.
Though these vaccines have shown efficacy, some have side effects including viral shedding.
RESULTS: Approximately 50% of challenged individuals developed symptoms and viral shedding consistent with clinical disease.
However, our outcome of interest was the ability of these anti-AIV vectors to inhibit infectious viral shedding.
This is known as viral shedding.
Evidence shows that viral shedding (presumed to correlate with infectivity) peaks shortly after the peak in symptoms [20]; delay between symptoms appearing and the beginning of antiviral treatment and prophylaxis thus coincides this period of maximum infectivity.
Homosubtypic immunity may fully abrogate clinical symptoms and viral shedding from the intestinal tract, and drastically reduce viral shedding from the respiratory tract.
Viral shedding, antigen distribution in tissues, and survival time did not differ between the three populations.
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