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Maximum tumor uptake was reached at 1 h post injection (p.i).
Erdi et al. suggested 42%% of the maximum tumor uptake intensity as a proper contouring value in phantom studies [3].
Remarkably, PA reached maximum tumor uptake enhancement at the 30 μg dose already, whereas TO reached half as high tumor values at the corresponding 10-fold molar dose of 150 μg.
The maximum tumor uptake of 177Lu-m11B6 was higher than previously seen with 111In-m11B6, probably due to the use of a higher antibody dose (30 versus 20 μg) [17].
A biphasic relationship between uptake in receptor-positive organs and injected peptide mass has been reported, with maximum tumor uptake reached between 10 – 100 pmol/mouse (Bernhardt et al. 2003; de Jong et al. 1999; Notni et al. 2016).
Similarly Bernhardt et al. showed > 70% of maximum tumor uptake with 111In-pentetreotide (GOT1 cell model) when the tracer was injected between 6.4 – 664 pmol/mouse (Bernhardt et al. 2003).
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Maximal tumor uptake of the 177Lu-labeled RIC was observed at 24 h with an ID/g of 14.43 while maximum uptake for the 67/64Cu-labeled 67/64Cu-labeled 8 h.
The maximum Colo16 tumor uptake was 11.32 ± 2.48%ID/g at 48 h p.i., and the T/Bs increased to 1 (Figure 7).
In order to identify the maximum tumor F-FDG uptake large ellipsoid regions of interests were drawn around the whole tumor area and organ, respectively.
Regions of interest were hand-drawn around each tumor and within dorsal cervical muscles, to determine maximum and average tumor uptake (Tmax and Tav), and average muscle uptake (M).
PET imaging revealed rapid tumor uptake (maximum uptake of ∼12% ID/g at 4 h postinjection) of Sc CHX-A″-DTPA Cetuximab-Fab with excellent tumor-to-background ratio, which might allow for Sc CHX-A″-DTPA Cetuximab-Fabre clinical Sc CHX-A″-DTPA Cetuximab-Fab
More suggestions(15)
maximum metal uptake
maximum chromium uptake
maximum tumor burden
maximum water uptake
maximum tumor resection
maximum fluoride uptake
maximum tumor volume
maximum hydrogen uptake
maximum phenol uptake
maximum adsorption uptake
maximum tumor shrinkage
maximum tumor reduction
maximum glucose uptake
maximum tumor pressure
maximum tumor extent
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