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First, to minimize side effects caused by high concentrations of the chemicals, the maximum treatment concentration of each chemical compound was defined as the concentration that produced a slight delay in the growth rate of wild-type yeast cells (approximately 10% of control samples).
The SF50 was not reached for five cell lines at the maximum treatment concentration of 50 µM olaparib.
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In order to dissolve the propolis extracts in the culture medium, a maximum of 10 μL/mL of DMSO was used to obtain the highest propolis treatment concentration.
Treatment concentration was.1%.
Maximum treatment duration was 14 days.
aPercentage of cell viability after 24 h incubation of maximum concentration treatment (200 μg/ml) of each compound.
At the Tmax (2 h) after oral dosing the conventional treatment, mean maximum plasma concentration (Cmax) of enrofloxacin was 3.0 μg/mL, which is comparable to other literature reports [ 25].
To compare maximum concentrations between treatment groups median instead of mean concentration values were used due to the comparatively high variability of single values.
To determine the rate of incorporation, 95% of the value of the asymptote was used to define the maximum FA concentration for each treatment group.
Evaluations of the patients' back pain will be conducted at baseline and 30 minutes after treatment (Table 1), because the pain relief and improvement in motion due to MSAT appears immediately after the treatment and the maximum plasma concentration for diclofenac is about 10-20 minutes after intramuscular injection.
This study shows that both maximum on-treatment bilirubin concentration and bilirubin increase from baseline were strongly associated with the UGT1A1 TA-repeat polymorphism.
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