Sentence examples for maximum toxicity grade from inspiring English sources

CR status did not correlate with maximum toxicity grade (Supplementary Table 2).

Adverse events were based on the maximum toxicity grade for each type of event.

The maximum toxicity grade of the majority of AEs was Grade 3 or less, and most resolved without sequelae.

The maximum toxicity grade per patient was grade 3 in 21 cases (77.8%) and grade 4 in 4 cases (14.8%).

The maximum toxicity grade of the majority of frequently reported AEs was Grade 1 or 2. Grade 3 diarrhea was reported at a frequency of 20%%, contributing to a high overall frequency (62 %) of AEs with a maximum toxicity Grade of 3. AEs of neutropenia also reached a maximum toxicity Grade of 3 for 22 % of patients.

Table 4 summarizes the frequency of these solicited toxicities by maximum toxicity grade as evaluated by the physicians, for all patients, by baseline KI status and by age group.

The following solicited toxicities were collected as maximum toxicity grades (none, Grade 1/2, Grade 3/4) at each visit: neutropenia, febrile neutropenia, mucositis, stomatitis, pharyngitis, fatigue, asthenia, nausea, vomiting, diarrhea, and rash/desquamation.

A total of 1149 cycles of chemotherapy were administered (575 CIP, 574 CEP), and toxicity data were available for 85% of the cycles; maximum toxicity grades were available for all the patients.

Although hyperbilirubinemia was observed in 34.6% of patients, most events were of a low grade and only 1 patient permanently discontinued treatment due to hyperbilirubinemia with a maximum toxicity of grade 2. Because cardiotoxicity is a known concern with HER2 inhibitors [9], [31], [32], it is notable that no cases of LVEF decreases or cardiac failures were observed in this study.

No significant myelosuppression occurred with the maximum toxicity being Grade 2 anaemia in 30% of patients.

The maximum observed toxicity grade was recorded for all patients (N = 58), according to NCI-CTCAE v3.0.