Sentence examples for maximum tolerated doses from inspiring English sources

Furthermore, the maximum tolerated doses for PLD in different combination therapies on a 3-doses-a-week schedule were 30 mg/m2 [ 22], 35 mg/m2 [ 23] or 45 mg/m2 with PPE/mucositis occurring at 40 mg/m2 [ 24].

The presence of patient heterogeneity in dose finding studies is inherent (i.e. groups with different maximum tolerated doses).

With the exception of morphine, which provided slight benefit, the latter drugs did not provide more relief at the maximum tolerated doses.

Maximum tolerated doses (MTD) of PAMAM dendrimers as a function of size and surface functionality were established and clinical signs of toxicity monitored.

Conclusion: 90Y Zevalin administered to NHL patients at non-myeloablative maximum tolerated doses delivers acceptable radiation absorbed doses to uninvolved organs.

This phase I study of high dose ketoconazole and docetaxel was designed against castration resistant prostate cancer to determine the maximum tolerated doses, side effects, and pharmacokinetic interaction of co-administered docetaxel and ketoconazole.

Thus, for subjects diagnosed after the age of 20, maximum tolerated doses of combination therapies should be prescribed in order to reduce the risk of CHD.

Maximum tolerated doses were given daily for 3-7 days.

Most were inactive at maximum tolerated doses, but nitrofurazone showed reasonable activity.

These early trials are designed to determine safety and maximum tolerated doses.

Daily and weekly maximum tolerated doses (MTDs) were 7.5 mg and 70 mg, respectively.