Sentence examples for maximum tested dose from inspiring English sources

This dose represented 17% of the maximum tested dose in rats and 10.2% of that tested in Beagle dogs; these maximum tested doses were neither lethal nor toxic.

Their analysis focused on an R value of 1.8 and a small stockpile sufficient to vaccinate 10% of the population with the maximum tested dose in a multitype-vaccinated population with uniform mixing.

Since the maximum tested dose (1000 mg/kg diet) did not produce any macroscopically evident adverse effect, we precautionally used in all studies the dose of 800 mg/kg diet, which is just 3.2 times higher than the therapeutical dose in humans.

Figure 2 shows attack rates for dose-response pairs with the same assumptions as in Figure 1 (R0 = 2, 20% coverage at the maximum tested dose) but with vaccination occurring when the cumulative attack rate has reached 0.01% (panels A and B) and 1% (panels C and D) of the population.

In the subgroup analysis, the two studies were assigned to a dose group according to the maximum dose tested in that study.

If the MTD was not exceeded within the planned dose levels, MTD was defined as the maximum dose tested.

If the MTD was not exceeded within the planned dose levels, the MTD was defined as the maximum dose tested.

Both were found to be safe up to 2000 mg/kg which was the maximum dose tested.

ApoE COG 133 peptide caused a significant reduction in the intestinal MPO levels at the maximum dose tested (3 μM) (p <0.05).

However, when the maximum dose tested (1,800 mg kg-1) was administered as 6 daily fractions of 300 mg kg-1 each, no increase in artificial metastases was detected.

The IC50 values reported in Table 1 show a very low susceptibility of primary cell cultures, composed of resting cells and macrophages from buffy coats to the effects of fullerenes 1 and 2. These cells showed no toxicity up to 72 h exposure to the maximum dose tested, and it was not possible to precisely extrapolate the IC50 in these cell lines.