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A supercritical fluid extraction (SFE) process was optimized by employing a 5-level-3-factor central composite design to achieve maximum target response values for total extract yield, ST yield, Reb-A yield and total phenolic content of 15.85%, 95.76 mg/g, 62.95 mg/g and 25.76 mg GAE/g, respectively.
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A 5-level 3-factor central composite design was used to optimize microwave-assisted extraction (MAE) to obtain maximum yield of target responses as a function of extraction time (X1: 1–5 min), ethanol concentration, (X2: 0–100%) and microwave power (X3: 40–200 W).
Under the proposed experiment condition, 0.1 μg/ μL of IPC (green dotted line in Figure 2(a)) could be considered as an optimal probe density for the maximum target hybridization rate and its signal response.
To mitigate this problem, the partial response maximum likelihood (PRML) receiver with a specific target response is widely used; it has acceptable performance for a reasonable realization complexity.
Therefore, identifying the maximum effective dose, defined as the lowest dose that achieves a pre-specified target response and beyond which improvement in the response is unlikely, becomes increasingly important.
Furthermore, the equalized maximum likelihood (EML) receiver is proposed, and its performance is improved because of the optimized target response.
According to Hansen, we need to focus on a maximum target of 1C.
No deviation from the maximum target dose (195UI) was allowed.
A cap is established, however, for maximum target budget.
The maximum target identity between possible target pairs was also relatively low (sequence identity: 23%).
I want a LOCAL targeted response.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com