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The maximum single dose was 15 g.
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47 Among i.v. preparations, the less stable formulations, such as iron gluconate, are more prone to reduction, with greater risk of oxidative stress, so that the maximum single dose is smaller.
40 Although a maximum tolerated single dose was not established, multiple dosing at 10 mg/kg resulted in better objective responses and durable stable diseases than was observed in the single high dose group.
A single dose was lethal.
The starting dose was 50 mg and the maximum single dose to be administered was not to exceed 1600 mg.
The recommended maximum single dose of levobupivacaine is 150 mg.
The maximum single dose of paracetamol for children is 15 mg per weight (kg) of the child.
The adalimumab dose was 24 mgivengiven as a subcutaneous injection every 14 days, with a maximum single dose of 40 mg.
Our preliminary studies showed that, of the various doses of AECHL-1 (0.5 to 5 mg/kg) injected intraperitoneal in C57BL/6 mice, the maximum tolerated dose was a single dose of 0.5 mg/kg that showed no obvious sign of toxicity when observed for one month.
Based on the results of the Phase I study of single administration of nedaplatin, the maximum tolerated dose was established as 120 mg/m.
The maximum tolerated dose was 0.93 mg/kg.
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