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The spectrum emission study revealed a maximum signal peak at 450 nm for aspartate and glutamine.
For glycine, taurine, and GABA, the maximum signal peak was at 448 and for glutamate at 452 nm.
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Interestingly, with the exception of H3 turnover, all of the properties present maximum signal peaks at ~-60 bp from the dyad of the +1 nucleosome (~13 bp from the upstream border of the +1 nucleosome).
The dynamics of a typical intracellular signal are defined by several properties: the time of the maximum signaling peak, the duration of the signal and the peak amplitude 16.
The maximum EMG signal (peak filtered EMG amplitude) of the 3 MVCs was used for subsequent normalization.
SNR was estimated as the ratio between the maximum signal measured at the peak of the spike (over all channels) and the standard deviation of some baseline data (2 s of data showing normal traces with no epileptic activity).
In semi-quantitative analysis, the signal-intensity time curves were used to determine the time to peak (TTP), maximum signal enhancement (Smax) and the area under the curve (AUC) for the total curve and also for the first 60 s (AUC60).
SNPs were ranked on normalised peak scores (maximum signal strength across any cell line) from genome-wide DNase HS data assayed in 125 cell types (wgEncodeRegDnaseClusteredV2) [ 25, 26].
Perfusion parameters were defined as follows: peak enhancement (maximum signal intensity reached during the transit of the bolus, expressed in % where 100% means the maximum), TTPceus (time of arrival of contrast agent post-injection to its maximum peak enhancement value).
By using different DCE parameters (including rate transfer constant (Kep), peak time, maximum signal intensity, and extracellular-extravascular volume (Ve)), Liu et al. showed the potential of dynamic contrast enhancement (DCE) MR in differentiating pancreatic ductal adenocarcinoma (PDA) from non-PDA lesions [ 65].
Additionally, a first-order exponential signal decay term was fit to each metabolite peak from the point of maximum signal over the course of signal decay.
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