Subjects were counted once for maximum severity of an event, preferred term and system organ class.
Independently of their physicians, patients rated the severity of their complaints as they experienced them on a numeric rating scale (NRS, 0 = no complaints, 10 = maximum severity of complaints the patient could imagine for this disease) [ 12].
Figure 6e, f display the spatial distribution of statistics for extreme events, considering the maximum duration and the maximum severity of droughts in China.
Similarly substituting covers for wheat during the build-up phase of an epidemic may be an equally viable strategy but, to gain maximum advantage, the cover needs to coincide with maximum severity of take-all, which is difficult to predict.
Mean maximum severity scores for EAE were done using the following grading criteria: Grade 1. limp tail; grade 2. limp tail and weak hind limbs; Grade 3. hind limb paralysis; Grade 4. fore limb paralysis; Grade 5. moribund; Grade 6. death.
Severity of local and solicited adverse events was compared using cumulative logit models with main effects for dose group and CPG, with each participant scored for maximum severity events as follows: severity = 0 (no AE observed), severity = 1 (mild), severity = 2 (moderate) and severity = 3 (severe).
Score components include shock (0 to 4 points), clinical history (MI, stroke, angina; 0 to 2 points), age (0 to 3 points), ECG findings (0 to 3 points), congestive heart failure (0 to 3 points), and Charlson Comorbidity Index (0 to 6 points) for a maximum severity score of 21 points [ 19].
A standard scoring system based upon redness and swelling of each paw (ranging from 0 to 4 for each paw, thus resulting in a possible maximum severity score of 16) was used for the assessment of disease severity.
The severity of headache days was determined by the maximum severity across all the headache reports for the day.
Average severity was 2.6 for children and 2.4 for caregivers on a 1 to 4 scale (maximum severity).
