Sentence examples for maximum serum levels from inspiring English sources

Maximum serum levels of ranibizumab following a single intravitreal injection in the monkey have been shown to be 150 ng/mL.

Maximum serum levels are reached 2 6 hours after ingestion, and result in fluctuating serum T levels (for a review see Behre et al 2004).

Others have reported maximum serum levels of cetuximab of ~65 μg/ml and ~400 μg/ml cetuximab after injection of doses of 0.25 mg and 1.0 mg into mice respectively [ 28, 39], similar to those reported in patients.

Pharmacokinetic studies showed a rapid and prolonged absorption of denosumab after subcutaneous injection, starting 1 h post-dose and reaching maximum serum levels as late as 21 days later [ 44, 45].

However, for those samples in which a positive result was obtained, maximum serum levels were generally observed three hours after the subcutaneous injection of F8-IL10 with serum levels of about 20 ng/ml.

The maximum serum level observed was 11,040 pg/ml and the disappearance rate indicated a half-elimination time of 1 hour 34 minutes.

Curcumin revealed poor bioavailability has been well recognized by earlier finding [ 164] and a study reported that 10 mg/kg of curcumin given intravenously to rats yield a maximum serum level of 0.36 ± 0.05  μg/mL, whereas 500 mg/kg of curcumin administered orally only yielded a 0.06 ± 0.01  μg/mL maximum serum level [ 180].

The studies of ADA in rats were limited, and it has been reported that the maximum serum level of ADA was reached after an average of five days, after subcutaneous administration in humans [ 44].

Grimnes et al. [ 20] found that excessive vitamin D supplementation (inducing mean maximum serum level 74 ng/ml) is associated with lower BMD and decrease of bone remodeling in osteopenic post-menopausal women.

The concentration of PCB-77 was based on the maximum serum level of PCB-77 (0.84 µg/g, converted to ≈ 3 µM) measured in experimental mice, as described above, at week 2 after administration of PCB-77 (50 mg/kg).

In order to control for the difference of ethanol absorption between males and females the formula described by Wittmann et al. [ 34] was applied: Absorbed amount (mg) = body mass (kg) × r × maximum serum level (mg/L), where r is 0.7 for males, and 0.6 for females, respectively.