The system was designed to track a desired end-tidal CO2 pressure (PaCO2), to find a PEEP leading to maximum estimated respiratory system compliance and to maintain the arterial oxygen saturation (SaO2) at an optimal level.
We propose a procedure to estimate the model parameters of presented nonlinear Resistance-Capacitance (RC) and the widely used linear Resistance-Inductance-Capacitance (RIC) models of the respiratory system by Maximum Likelihood Estimator (MLE).
Respiratory system static inflation end-inspiratory compliance (Crs), minimum (Rint) and maximum (Rrs) resistance of the respiratory system and the difference between Rrs and Rint (Δ R) were computed according to standard formulas and procedures [ 11, 12].
The insect tracheal system is a unique respiratory system, designed for maximum oxygen delivery at high metabolic demands, e.g. during activity and at high ambient temperatures.
The final results showed that both of the individual treatments were effective in reducing the maximum resistance and elastance of the respiratory system and lung parenchyma when challenged with antigen, suggesting that Rho-kinase inhibition or corticosteroid treatment modulate the constriction of the airways and lung parenchyma.
Blood gases were sampled again, and MAP, MPAP, and CVP, as well as FRC and compliance of the respiratory system as obtained from the maximum slope of the expiratory PV loop, were recorded [ 25].
The compliance of the total respiratory system was measured between zero and maximum airway pressure values on the inflation (Crsinf) and deflation (Crsdef) limbs of the P-V curves.
In a surfactant-depletion model of ALI, during a decremental PEEP trial following a RM there was always a PEEP level at which the respiratory system reactance measured by FOT reached a maximum.
However, considering that the form and function of the respiratory system may be adjusted to the demands of maximum exertion [37], maximal metabolic rate (MMR) may represent a more appropriate measure of metabolic demand.
A decremental titration of PEEP aimed to yield maximum dynamic compliance was associated with an improvement in oxygenation, dynamic respiratory system compliance and unloading the right ventricle while not affecting the left ventricle.
