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Maximum release is displayed by the Si-CHA sample after the period of 14 days.
The maximum release was 74% at pH 9 after 7 days.
The maximum release was found to be 90% in simulated intestinal fluid (SIF).
Addition of both PC and glycerol caused the maximum release (55%).
Maximum release and distribution in tumors were achieved using 5 nm AuNP incorporated into the NPD.
The devices showed a strong pH-dependent swelling behaviour, allowing a maximum release at pH 7.4.
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Percentage of specific release was calculated as (experimental release-spontaneous release)/(maximum release-spontaneous release) ×100.
All samples were run in triplicate, and results were calculated as: 100× (experimental release-spontaneous release)/(maximum release-spontaneous release).
The percentage of specific cytotoxicity was determined using the formula: 100×[(release in assay-spontaneous release)/(maximum release-spontaneous release)].
Percent specific lysis was determined from the following formula: 100×((experimental release-spontaneous release)/(maximum release-spontaneous release)).
Specific lysis was determined as: (experimental release-spontaneous release)/(maximum release-spontaneous release) × 100%.
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