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This combination leads to the optimum glucose consumption rate and maximum product formation.
The determination of a suitable culture age during growth of P. aeruginosa in medium for maximum product formation was accomplished by harvesting cells in various stages of growth and employing them for myrcene biotransformation.
As a consequence, maximum product formation does not always correlate with maximum biomass concentration.
In general, no defined medium was established for the best production of any metabolite because the genetic diversity present in different microbial sources causes each organism or strain to have its own special conditions for maximum product formation.
Since production of acetoin and 2,3-butanediol is generally accepted to be a growth-associated phenomenon, the conditions for the maximum product formation must approximately be the same as those for the maximum biomass yield [ 31].
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Recombinant protein expression was in the form of inclusion bodies with a maximum specific product formation rate (qp) of 63.5 mg g−1 DCW h−1 at a dilution rate (D) of 0.3 h−1.
Maximum rate of product formation (h−1).
Surprisingly, increased cell concentration decreased the maximum specific rate of product formation.
Hence, a metabolite-centric view on flux distributions can guide metabolic engineering, where the goal is often to optimise split ratios between pathways leading to product formation, biomass production, and energy generation in order to achieve maximum product yield [ 51, 52].
Although GQ basically supports growth-decoupled product formation, AQ enables maximum cell-specific peaks of productivity and accelerates growth.
The measurable effects of stress include reductions in growth rate, maximum cell density, substrate uptake rate, product formation rate, yield, etc., and tolerance broadly refers to the cells' ability to resist these effects.
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maximum product value
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maximum clot formation
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maximum hydrocarbon formation
maximum nitrate formation
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