Sentence examples for maximum plasma level from inspiring English sources

These values correlate well with maximum plasma level concentrations used in anticancer treatment and confirm that the 3D-microtissue assay can provide relevant information on therapeutic potential.

In several studies, there was increased proliferation of tumor-cell lines on Epo addition, but with supraphysiological Epo levels that were 10- to 1,000-fold 1,000-foldan the maximum plasma level observed in patients receivingreaterved Epo doses.

After administration of a single oral dose of luseogliflozin, its maximum plasma level (Cmax) and area under the concentration time curve increased in a dose-dependent manner, and no food effects were observed on pharmacokinetics.

The median area under the plasma concentration curve (AUC) obtained with the oral formulation was 226 ng ml-1h-1 (range 91-750), and the median maximum plasma level (Cmax) was 50.5 ng ml-1 (range 24.7-199.6) after a dose of 8 mg.

The difference in bioavailability between the two drugs should ideally lie within the therapeutic bioequivalence interval (the 90%% confidence interval of the ratio of a log-transformed test to reference mean area under the curve (AUC), which shows drug absorption, and maximum plasma level during drug absorption (Cmax) values falling within the range of 80 125%%) [ 4].

BPR1J-097, after a 3.4 mg kg−1 i.v. dose administered to rats, achieved a maximum plasma level maximum concentration of 7.1  �� (3670 ng ml−1) at 2 min of dosing and, at 24 h after dosing, the estimated BPR1J-097 plasma concentration remained at a concentration of 1 ng ml−1 (1.9 n).

Maximum plasma levels of N901-bR ranged from 72-371 ng/mL.

The plasma samples obtained from the volunteers were investigated using the previously obtained calibration graph or regression equations and the results obtained are shown in Figure 7 showing maximum plasma levels are reached after 3.5 hours for SUL and veratic acid.

These doses have been used as the maximum plasma levels measured in a controlled trial of vitamins C and E supplementation for preventing preeclampsia [23].

Maximum plasma levels (413 789 ng/mL) were associated with almost complete (>95%%) suppression of arrhythmias [ 47– 51].

Consequently, the maximum plasma levels were much higher (0.62%) in the 3-h infusions than when using longer infusion durations.