Sentence examples for maximum plasma drug from inspiring English sources

The maximum plasma drug concentration (Cmax) of total methoxyflavones was 218.08 ng/ml with Tmax at 8 h.

In vivo pharmacokinetics experiments showed that three formulations had comparable maximum plasma drug concentration (Cmax), and the time (Tmax) to reach Cmax of lacidipine tablet, which was prepared by Soluplus, as polymer was slower than other two formulations in consistency with the in vitro dissolution rate.

The maximum plasma drug concentration (C max) and the corresponding time to achieve this value (t max) were noted directly.

The maximum plasma drug concentration (Cmax) and time to maximum concentration (Tmax) were taken directly from the observed data.

In addition, IPX066 maintained levodopa plasma concentrations above 50%% of the maximum plasma drug concentration (Cmax) for a longer duration than IR CD-LD (4 vs. 1.4 h).

Since pharmacokinetics are affected by body weight, we expect maximum plasma drug concentrations to vary according to both patient age and weight.

However, not unexpectedly, maximum peak plasma drug concentration (Cmax) was higher and the mean time to Cmax (tmax) shorter in those receiving galantamine-IR.

After ingestion, participants waited for 60 min to ensure maximum peak plasma drug concentration according to levodopa pharmacokinetics (Khor and Hsu 2007).

However, after bcrp, mrp1 or mrp3 knock-down, the cisplatin IC50 doses were similar or lower than the maximum possible plasma drug concentration in all of the examined cell lines.

The difference in bioavailability between the two drugs should ideally lie within the therapeutic bioequivalence interval (the 90%% confidence interval of the ratio of a log-transformed test to reference mean area under the curve (AUC), which shows drug absorption, and maximum plasma level during drug absorption (Cmax) values falling within the range of 80 125%%) [ 4].

For most drugs, this range is wide enough, and the maximum plasma concentration of the drug (Cmax) and the area under the plasma concentration time curve (AUC) achieved when the recommended doses of a drug are prescribed lie sufficiently above the minimum therapeutic concentration and sufficiently below the toxic concentration [ 2, 3].