Sentence examples for maximum permeability coefficients from inspiring English sources
By trend, freshly excised ventral skin of X. laevis was more permeable to both test compounds than dorsal skin with mean maximum permeability coefficients of 4.7 × 10−3cm/h for caffeine and 3.0 × 10−3cm/h for testosterone and 3.0 × 10−3cm/h for caffeine and 1.3 × 10−3cm/h for testosterone, respectively.
Maximum permeability coefficients of 110 × 103 Barrer and 27 × 103 Barrer for carbon dioxide and helium, respectively, were found to occur in membranes of ∼750 nm thickness.
An Additional file shows individual maximum permeability coefficients in detail (see Additional file 1).
Maximum permeability coefficients of this work are shown by a boxplot diagram (Fig. 2).
Maximum permeability coefficients which are independent of exposure duration were analyzed statistically as they represent comparable kinetic parameters (Fig. 2).
Average maximum permeability coefficients of amphibian dorsal and ventral skin measured in our study were 37 × 10−4cm/h and 19 × 10−4cm/h for caffeine and testosterone, respectively.
However, according to Marzulli classes [26], both test compounds would be classified as being 'fast' permeating substances across freshly excised skin with a maximum permeability coefficient of less than 6 × 10−3 cm/h.
Accordingly, the kinetic parameters: a maximum absorption rate of 12.1 ± 1.2 µg/(cm2 h) and a maximum permeability coefficient of 3.0 ± 0.3 × 10−3cm/h for freshly excised dorsal skin, which are less than half of the corresponding parameters for caffeine permeation across frozen stored skin.
On the basis of the absorption-time profiles, kinetic parameters were calculated [the steepest slope between two time points represented the maximum absorption rate (maxAR) in µg/(cm2 h] and division of maxAR by the applied concentration of the test substance provided the maximum permeability coefficient (maxKp) in cm/h).
The ratios of maximum and minimum permeability coefficients were found in the range of 1.4 1.7 for different mixtures.
The permeability coefficients for water (Pf) and glycerol (Pgly) transport were evaluated using the analysis described previously53.
