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The motif size was set to 10 and a maximum parsimony score of 2 was used.
When multiple trees are found with the same maximum parsimony score, the "extended majority consensus" of those trees is returned.
For example, the MCC maximum parsimony score dropped from 0.529 to 0.451 when the total rate was allowed to vary (ER_gVrl_1 vs. VR_gVrl_1).
The LS coefficient, as well as the ML function value or the Maximum parsimony score, can be used as an estimate of how close the distance matrix obtained from the pseudo-replicated sequences (or the set of pseudo-replicated sequences, in the case of ML or MP) is to the space of trees.
Usually a pairwise analysis of genomes in a set is carried out with a metric being computed that reflects the similarity between the genomes, this can be done using a maximum parsimony score, a threshold parsimony score (e.g. [ 14]) or deriving a phylogenetic distance.
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Such weights could be an average of bootstrap scores of the tree's internal branches, a maximum parsimony or maximum likelihood score or a Bayesian posterior probability estimate.
At the opposite end, maximum parsimony yields the highest scores for r2 and slope, showing the comparative robustness of this method against variations in the outgroups chosen –parsimony uses outgroups basically to determine character-state polarity.
AI: Association index, PS: Parsimony score, MC: Maximum monophyletic clade size.
The association index, parsimony score, and maximum monophyletic clade statistics provided strong support (p<0.01) that strains from Venezuela cluster by location, suggesting that YFV is maintained for long periods within Venezuela.
To assess the strength of this structure in a more quantitative manner, we calculated three summary statistics (association index AI, parsimony score PS and maximum monophyletic clade size MC) describing the correlation between the geographic and phylogenetic relationships from the posterior distribution of genealogies generated by the Bayesian coalescence analysis.
Estimating Association Index (AI), Parsimony Score (PS), and Maximum Clade number (MC) statistics tested the extent of geographic structure in BaTS [ 63].
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