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This PID controller satisfies the criteria of minimum integrated absolute error (IAE) and maximum of sensitivity (Ms).
The criterion of optimization is the maximum enhancement of the evanescent field or maximum of sensitivity for refractive index variations.
We defined the ideal cut-off point by maximizing the conditional Youden score (i.e., maximum of sensitivity and specificity).
Surprisingly, we observed the reverse, as it was the C-terminus fusion that produced no BiFC, even under high levels of protein expression and confocal parameters rose at their maximum of sensitivity (Additional File 3).
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The receiver operating characteristic (ROC) curve was used to select the optimal cutoff value according to the maxima of sensitivity and specificity to distinguish CIN3+ (including CIN3, CIS, SCC, AC and ASC) and CIN2− (including normal controls, CIN1 and CIN2) patients [ 30].
Moreover, the proposed PID tuning method includes a robustness specification based on the maximum peak of sensitivity function that enables the user to explicitly address the trade-off between performance and robustness.
This result shows that to approach the maximum value of sensitivity, biosensors with long lengths must be used.
This differential sensor design therefore should eliminate the parasitic resistance effects and give the maximum value of sensitivity.
It can consequently be concluded that the differential sensor design presented here has eliminated the detrimental effects of parasitic resistance and delivered the maximum value of sensitivity that is possible for a given nanoribbon doping concentration.
Optimal thresholds were identified as the maximum sum of sensitivity and specificity calculated at each observed delta Ct value.
* Denotes the maximum sum of sensitivity and specificity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com