Sentence examples for maximum observed plasma from inspiring English sources

The maximum observed plasma concentration (Cmax) and the time taken to achieve this maximum level (tmax) were directly obtained from the curves.

The effect of these non-specific hemostatic agents for reversal of apixaban concentrations measured in patients after prophylactic doses (maximum observed plasma concentration 62 ng ml-1 [4]) remains unclear.

Plasma concentration time profiles exhibiting a wide range of tmax and maximum observed plasma concentration (Cmax) were obtained from superposition of the simulated IR and ER profiles based on a linear IVIVC.

The following pharmacokinetic (PK) parameters were determined: area under the plasma concentration-time curve from time zero up to the last quantifiable concentration (AUC0-tlast), maximum observed plasma concentration (Cmax), time of maximum observed plasma concentration (tmax).

AUC: Area under the concentration-time curve; CL: Clearance; Cmax: Maximum observed plasma concentration; ESRD: End-stage renal disease; LC-MS/MS: Liquid chromatography-tandem mass spectrometry; OC: Oseltamivir carboxylate; PK: Pharmacokinetic; Tmax: Time to reach maximum observed plasma concentration.

Pharmacokinetic parameters for both free and VEGF-bound aflibercept were plasma concentrations before starting infusion at each treatment cycle (Ctrough) and the maximum observed plasma concentration (Cmax).

Pharmacokinetic parameters including the area under the concentration time curve (AUC) and the maximum and minimum observed plasma concentrations (Cmax and Cmin) were estimated using standard noncompartmental methods with WinNonlin software (version 5.1.1, Pharsight Corporation, Mountain View, CA).

Figure 3 presents the maximum observed olanzapine plasma concentrations during the events by dose.

Using this model, an LS mean ΔΔQTcP of 0.51 ms, with a two-sided 90% CI of −1.08 ms, 2.09 ms was estimated at the maximum observed steady-state plasma exenatide concentration (627 pg ml−1).

The mean area under the concentration-time curve and the maximum observed concentration AUC and Cmax of plasma exenatide concentrations during 8 h post-dose were not significantly different between groups.

Mean pharmacokinetic parameters in 14 patients in whom plasma assay data are available were: Maximum observed concentration = 30.7 ng ml-1; terminal phase half-life = 8.96 h; total body clearance = 0.376 (1 h-1) kg-1; apparent volume of distribution = 2.85 l kg-1.