Sentence examples for maximum mutation rate from inspiring English sources

The maximum mutation rate for noncoding, nonrepetitive genomic regions in the human genome has been determined as 0.99×10−9 substitutions per nucleotide site per year [35] and in such sequences approximately one mutation gets fixed every 200,000 years.

ϕ controls the maximum mutation rate at a locus.

Each increase of ϕ by 1 increases maximum mutation rate by an order of magnitude.

For example, although maximum mutation rate is 1 × 10 − 5 when ϕ = 3, maximum mutation rate is 1 × 10 − 4 when ϕ = 4. Mutation was symmetric, equally likely to increase or decrease allele size.

In Figure 7 we show an example for the shortest target with μ = 0.13, i.e. above μ = 0.126, identified as the maximum mutation rate under which an individual based solution can be maintained.

In some fitness landscapes it also predicts the existence of a maximum mutation rate, called the error threshold, beyond which the quasispecies enters into error catastrophe, losing its genetic information.

With variable genome length it is not maximum mutation rates which increase genetic diversity as one would intuitively expect.

Because we did not allow the number or rate of TSG inactivation or oncogene activation to drop below a minimum threshold (the maximum mutation rates for activation/inactivation are set at 10−1), we observed an increase in the importance of TSG as a cancer suppression strategy in larger species.

Pinho et al. [ 15] used well-known and dated independent geological events in the Aegean [ 110] to estimate a maximum and minimum mutation rate for the ND4 mitochondrial fragment (and flanking tRNA-His) for the lacertid lizards of the genus Podarcis (0.0278 and 0.0174 mutation/site/million years, respectively).

First, with the simplification of neglecting back mutations, we calculate the error-threshold as the maximum allowable mutation rate for which the fittest genotype can survive.

The maximum spontaneous mutation rate is estimated at 3 X 10 -8); the equilibrium frequency of habituant cells in an otherwise nonhabituated culture is estimated at 5 X 10 -7).