There was no correlation between maximum motion magnitude and rating.
The three subjects with the largest maximum motion magnitude (11, 8, and 8 mm) and the only two PiB-positive patients amongst the seven subjects with maximum motion magnitude >4 mm were selected for further analysis.
Before motion correction, three of the five subjects were rated slightly blurred (8, 6, and 8 mm maximum motion magnitude, respectively) with no correlation between motion magnitude and rating.
Subject five with an 11-mm maximum motion magnitude before MC in (a) and after MC in (b).
The subject with the largest maximum motion magnitude is shown at the top and the subject with the lowest maximum motion magnitude (1 mm) at the bottom.
Navigators 2 6 (Nav2–Nav6) were rigidly registered to the first navigator (Nav1) using SPM [16], and the motion magnitude for a point in the frontal cortex (60 mm in front of the scanners center of FOV) was calculated and plotted for assessment of maximum motion magnitude.
Decreased blurring was seen in the two patients with a PiB-positive scan and in one of the PiB-negative subjects (Table 1) but not in the two other PiB-negative subjects with the same or larger maximum motion magnitude, even though one would expect motion blurring (and the effect of correcting for it) to be proportional to motion magnitude.
With a maximum motion of 0.35 mm in the DLS 5.0, the results and recommendations from sheep studies by Claes et al. [7] seemed to be realised.
Each subject was then asked to perform complete maximum motion of the lumbar spine once in each cardinal plane, and return to their neutral standing posture.
A car, after all, is a sort of four-wheeled avatar of the people who built it, and this car is clearly the work of a small group of very talented, very focused individuals bent on extracting maximum motion from each horsepower.
