It corresponds to the forced expiratory flow at 50%% (FEF50) and correlates highly with the maximum mid-expiratory flow FEF25-755 %) [ 2].
Our analyses included forced expiratory volume at 1 sec (FEV1; milliliters), forced vital capacity (FVC; milliliters), peak expiratory flow rate (PEFR; milliliters per second), and maximum mid-expiratory flow rate (MMEFR; milliliters per second).
Gauderman et al. (2007) found that children who lived within 500 m of a freeway (motorway) had substantial deficits in 8-year growth of forced expiratory volume in 1 sec (−81 mL) and maximum mid-expiratory flow rate (−127 mL/sec, p = 0.03), compared with children who lived at least 1,500 m from a freeway.
Participants in the highest decile of 1,4-DCB concentration had decrements of −153 mL [95% confidence interval (CI), −297 to −8] in forced expiratory volume in 1 sec and −346 mL/sec (95% CI, −667 to −24) in maximum mid-expiratory flow rate, compared with participants in the lowest decile.
With urinary phthalate measures, we assessed the association between phthalate exposure and four pulmonary function parameters [forced vital capacity (FVC), forced expiratory volume at 1 sec (FEV1), peak expiratory flow (PEF), and maximum mid-expiratory flow] among the 240 adult Third National Health and Nutrition Examination Survey (NHANES III) participants with urinary phthalate data.
We compared the conventional surrogate marker of dysanapsis, maximum mid-expiratory flow to FVC (MMF/FVC), in SUBJECTS (FEV1/FVC < 70%, both the %FEV1 and the %FVC ≧100% in healthy non-smokers) (n = 25), in EMPHYSEMA (CT confirmed pulmonary emphysema, same spirometry results with SUBJECTS) (n = 55), and in CONTROLS (age- and height- matched, normal spirometry results) (n = 25).
FVC, forced expiratory volume in 1 second (FEV1), peak expiratory flow rate (PEFR), and mid expiratory volume (FEF 25 75%) values were recorded.
Gr.: group, FEV1: forced expiratory volume in one second; FVC: forced vital capacity; PEF: peak expiratory flow; MMEF: maximal mid expiratory flow; MEF75, MEF50 and MEF25: maximal expiratory flow at 75%, 50%, and 25% of the FVC respectively.
No significant difference was observed in % predicted values of forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC, peak expiratory flow (PEF) and maximal mid expiratory volume FEF25-755) betheen the photocopier operators and control subjects.
Forced vital capacity (FVC), FEV1 and maximal mid expiratory flow (MMF) were shown as arithmetic mean values ± SEM.
