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The maximum mean increase in FEV1after zafirlukast in these subjects, who were considered responders, observed after 2 h, was 0.221 (19.4%).
Zafirlukast, but not placebo, produced a significant (P<0.05) bronchodilation between 30 min and 4 h following administration, with a maximum mean increase in FEV1of 0.134 l (11.2%) above baseline after 2 h.
The maximum mean increase in range size was +35% in the foothills of the Great Central Valley in the PCM, A1 scenario.
A maximum mean increase in NPRS score of 3.0 was recorded just before removal of NGX-4010.
The maximum mean increase in heart rate from both the preantiemetic and postantiemetic/preromidepsin baselines occurred at the 6 h time point, at 18.2 and 20.0 beats per minute (bpm), respectively.
Blood pressure levels increased following administration of the NGX-4010 pandh and reached the maximum mean increase in systolic blood pressure of 11.8 mm Hg, 55 minutes after application.
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The maximum mean increases from the preantiemetic baseline for QTcF and heart rate were 10.1 msec (upper 90% CI, 14.5 msec) and 18.2 beats per minute, respectively.
(c) Maximum mean temperature increase (T max → ACCESS1.0, CSIRO-BOM, Australia, +3 °C).
The maximum mean (SD) increase in pulse was 9.9 (9.8) bpm (70 mg LDX group at 12.5 hours postdose) compared with 6.6 (12.9) bpm for the placebo group and 6.6 (13.6) bpm for all active doses of LDX combined at the same time point.
Maximum mean (SD) increases in pulse rate, SBP, and DBP (9.9 [9.8] bpm, 4.2 [9.2] mmHg, and 4.7 (8.5) mmHg, respectively) were all observed in the LDX 70-mg group.
Maximum mean (SD) increases from baseline in blood pressure were 4.2 (9.2) mm Hg for SBP (70 mg LDX group at 8 hours postdose), and 4.7 (8.5) mm Hg for DBP (70 mg LDX group at 8 hours postdose).
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maximum mean radiation
maximum mean grain
maximum mean strain
maximum mean discrepancy
maximum mean efficiency
maximum mean discount
maximum mean message
maximum mean square
maximum mean median
maximum mean cross-correlation
maximum mean curvature
maximum mean depth
maximum mean stress
maximum mean temperature
maximum mean deviation
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