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Maximum lipid arc on OCT was an excellent discriminator of fibroatheroma (area under the curve, 0.92; 95% confidence interval, 0.87 0.97) and TCFA (area under the curve, 0.86; 95% confidence interval, 0.81 0.92), with lipid arc ≥80° the optimal cut-off value.
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Lipid arc (LA) measurements were recorded within each frame and mean (LAmean) and maximum (LAmax) value calculated.
The maximum lipid yield, especially for oxygenated compounds was in the window of 150 250 °C.
Indeed, N-starvation does not influence lipid production, however, maximum lipid content (4.3 ± 0.17 g/L), lipid productivity (0.79 ± 0.01 g/L day) and lipid yield (175.56 ± 21.9 mg/g glucose) was obtained with MN supplementation (Table 2).
Maximum lipid content was obtained at 120 h of cultivation in all treatments.
Lipid index (LI) was defined as the mean lipid arc multiplied by lipid length [ 11].
There was no difference in lipid arc or lipid plaque length.
Intraclass correlation coefficients for intra- and interobserver reliabilities were 0.982 and 0.958, respectively, for the lipid arc, and 0.992 and 0.963, respectively, for the calcification arc.
Lipid index (LI) (mean lipid arc × length), fibrous cap thickness (FCT), and the prevalence of thin-cap fibroatheroma (TCFA) were assessed in both culprit and non-culprit lesions.
Whereas several OCT-derived plaque parameters are predictors for ACS, only mean lipid arc, lipid plaque length, presence of macrophages and minimal FCT were independent predictors.
In lipid-rich plaques (lipid plaque >90° in any of the cross-sectional images within the plaque) the lipid arc was measured at every 1 mm interval throughout the entire length of the lipid plaque and the values were averaged.
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