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A single maximum likelihood calculation on the (1/60) dataset using 32 processors for computing and the memory from 480 processors on the Altix system took approximately 25.5 hours and 30 Gb of memory per compute processor (data not shown).
Combining these data with our model, the model parameters can be estimated by maximum likelihood calculation.
Using three bands (red, green and near infrared), the image was processed using the maximum likelihood calculation for supervised classifications.
Base calls were made by a maximum likelihood calculation, computed as the product of the probabilities for each base at each position using uncertainties estimated during image analysis.
In addition to the work of Tan et al. (2006), exposure reconstruction for chloroform using PBPK modeling has appeared in Georgopoulos et al. (1994) and Roy et al. (1996) in the form of a maximum likelihood calculation.
For the expectation step, each MA was assigned a weight (possibility to belong to these two distributions), and then based on these weights, a maximum likelihood calculation updated the parameters of the two distributions.
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On the other hand, the maximum likelihood calculations all required a substantial amount of memory.
To perform maximum likelihood calculations efficiently would require hardware configured with substantially more memory per processor than the configuration cited in this paper.
PAUP*4b10 [ 57] was used to carry out the maximum likelihood calculations.
Maximum likelihood calculations were conducted to estimate fits to the Gompertz parameterization for each of the rapamycin survival tables.
As the full likelihood includes several integrals, the actual maximum likelihood calculations are performed discretely, grouping the data into sufficiently small time and tumor size intervals.
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