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The maximum lifespan reported in captivity was 27 years.
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However, SLFB lifespan reported so far is less than 200 cycles under normal flow conditions.
However, we found a significant negative correlation between the substitution rate and maximum lifespan as has been previously reported for mitochondrial synonymous sites across mammals [21].
One source reports the maximum lifespan as at least 15 years, while another source gives at least 19 years.
MsrA has been reported to extend lifespan by up to 70% through its over-expression in Drosophila melanogaster [24], while deletion of MsrA in mice was reported to decrease maximum lifespan by about 40% compared to wild type mice [25].
The spe-10 mutant did not show an increased mean or median lifespan as previously reported, although its maximum lifespan was extended considerably compared with wild-type.
The maximum lifespan of captive Hylobates has been reported to be 35.6 years [ 54], but this is an underestimate, as two of the wild subjects in our study exceeded that age, at 38.2 and 45.2 years, and a captive gibbon (H. muelleri) has been reported to have lived 60 years [ 55].
A recent study by Liu et al. (2013) reported that Zmpste24/Suv39h1 mice had a longer maximum lifespan than Zmpste24 mice – 29 weeks as compared to 40 weeks [ 54].
Studies on zebrafish used young adults of age 3 6 months and maximum reported lifespan for this species is 66 months (Gerhard et al., 2002) and there are no quantitative reports on age-dependent modulation of adult neurogenesis.
Previous studies of the highly homozygous GRZ strain reported a median lifespan of 9 weeks and a maximum lifespan of 13 weeks.
Since then, numerous studies have reported that lifelong caloric restriction (CR) extends mean and maximum lifespan and delays age-associated diseases in a wide variety of species [ 11, 12].
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