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The minimum and the maximum leukocyte count during ICU stay were determined.
One study found that the maximum leukocyte count, which has been seen 3 6 days after disease onset, correlated with fold-change in plasma creatinine [ 27].
Twenty of 86 patients (23.3%) had a minimum to maximum leukocyte count range >10 × 10 leukocytes/L, and 33 (38.4%) patients had a minimum to maximum leukocyte count range that included the cutoff of 15 × 10 leukocytes/L; therefore, a difference in timing of a single blood sample around diagnosis could have led to a different severity classification.
Maximum leukocyte count was significantly higher for patients with severe CDAD, and significantly more patients with severe disease had a maximum leukocyte count >20,000 cells/μL, minimum albumin level <2.5 g/dL, maximum glucose level >150 mg/dL, and serum creatinine level >2 mg/dL (Table 3).
Similarly, our logistic regression model showed the following variables to be significantly correlated with severe CDAD: maximum leukocyte count >20,000/μL, minimum serum albumin level <2.5 g/dL, and maximum serum creatinine level >2 mg/dL.
Maximum leukocyte count >20,000 cells/μL, maximum creatinine level >2 mg/dL, and minimum albumin level <2.5 g/dL were all independently associated with severe CDAD (p<0.05; Table 5).
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Maximum leukocyte counts were back to or below preoperative values between 4 6 days after surgery.
Maximum leukocyte counts and C-reactive protein levels measured during the ICU stay were recorded.
To describe the course of the illness, the maximum temperature, leukocyte count, platelet count and lymphocyte count data from every case were combined and averaged for each day of the illness.
When compared to patients with low IL-6, patients with high IL-6 had higher maximum blood leukocyte count (11.9 vs 9.0 × 10/l, P = 0.001) and urinary protein excretion (2.51 vs 1.68 g/day, P = 0.017), as well as a lower minimum blood platelet count (55 vs 80 × 10/l, P < 0.001), hematocrit (0.34 vs 0.38, P = 0.001), and urinary output (1040 vs 2180 ml/day, P < 0.001).
On a daily basis, research nurses collected the patient data (like maximum temperature, heart rate, leukocyte count, etc).
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